| 研究課題 |
赤血球置き換えSCIDマウスモデルの開発とこれを用いた住血原虫症の病態解析 |
| 著書・論文など |
1) Zamoto, A., Tsuji M., Kawabuchi T., Wei Q., Asakawa M., Ishihara C. U.S.-type Babesia microti isolated from small wild mammals in eastern Hokkaido, Japan. J. Vet. Med. Sci., 66(8):919 926, 2004.
2) Zamoto, A., Tsuji, M., Wei, Q., Cho, S-H., Shin, E-H, Kim, T-S., Leonova, G.N., Hagiwara, K., Asakawa, M., Kariwa, H., Takashima, I., Ishihara, C. 2004. Epizootiologic survey for Babesia microti among samall wild mammanls in Northeastern Eurasia and a geographic deversity in the b tubulin gene sequences. J. Vet. Med. Sci., 66(7):785-792.
3) Inokuma, H., Tsuji, M., Kim S-J., Fujimoto, T., Nagata, M., Hoshi, E., Arai, S., Ishihara, C., Okuda, M. 2004. Phylogenetic analysis of Theileria sp. from sika deer, Cervus nippon, in Japan. Vet. Parasitol., 120. 339-345.
4) Arai, S., Tsuji, M., Kaiho, I., Maruyama, H., Wei, Q., Okabe, N., Kamiyama, T., Ishihara, C. 2003. Retrospective seroepidemiological survey for human babesiosis in an area in Japan where a tick borne disease is endemic. J. Vet. Med. Sci., 65(3): 335-340.
5) Ishihara, C., Zamoto, A., Tsuji, M., Wei, Q., Azuma, I., Hioki, K. 2003. Erythrocyte-replaced mouse model for haemoparasite studies: Comparison of NOD/shi-scid and C.B-17/Jcl scid mouse upon acceptablility of human erythrocytes. J. Vet. Med. Sci., 65(8): 831-837.
6) Miyazaki, H., Matsuura, H., Yanagiya, C., Mizutani, J., Tsuji, M., Ishihar, C. 2003. Inhibitory effects of Hyssop (Hyssopus officinalis) extracts on intestinal glucosidase activity and postprandial hyperglycemia. J. Nutr. Sci. Vitaminol., 49: 346-349.
7) Okamoto, M., Furuoka, H., Horiuchi, M., Noguchi, T., Hagiwara, K., Muramatsu, Y., Tomonaga, K., Tsuji, M., Ishihara, C., Ikuta, K., Taniyama, H. 2003. Experimental transmission of abnormal prion protein (PrPsc) in the small intestinal epithelial cells of neonatal mice. Vet Pathol., 40(6):723-727.
8) Okamaoto, M., Hagiwara, K., Kamitani, W., Sako, T., Hirayama, K., Kirisawa, R., Tsuji, M., Ishihara, C., Iwai, H., Kobayashi, T., Tomonaga, K., Ikuta, K., Taniyama, H. 2003. Experimental vertical transmission of Borna disease virus in the mouse. Arch. Virol., 148: 1557-1568.
9) Cho, S.H., Kim, T-S., Lee, H.W., Tsuji, M., Ishihara, C., Kim, J.T., Wee, S.H., Lee, C.G., 2002. Identification of newly isolated Babesia parasites from cattle in Korea by using the Bo-RBC-SCID mice. Korean J Parasitol 2002 Mar;40(1):33-40.
10) Okabayashi, T., Hagiya, J., Tsuji, M., Ishihara, I., Satoh, H., Morita, C., 2002. Detection of Babesia microti-like parastite in filter paper-absorbed blood of wild rodents. J. Vet. Med. Sci.64: 145 147.
11) Tsuji, M., Wei, Q., Zamoto, A., Morita, C., Arai, S., Shiota, T., Fujimagari, M., Itagaki, A., Fujita, H., Ishihara, C., 2001. Human babesiosis in Japan: Epizootiologic survey of rodent reservoir and isolation of new type of Babesia microti-like parasite. J. Clin. Microbiol., 39:4316-4322.
12) Wei, Q., Tsuji, M., Zamoto, A., Kohsaki, M., Matsui, T., Shiota, T., Telford, III S. R., Ishihara, C., 2001. Human babesiosis in Japan: Isolation of Babesia-like parasites from an asymptomatic transfusion donor and from a rodent from an area where babesiosis is endemic. J. Clin. Microbiol., 39:2178-2183.
13) Saito-Ito, A., Tsuji, M., Wei, Q., He, S., Matsui, T., Kohsaki, M., Arai, S., Kamiyama, T., Hioki, K., Ishihara, C., 2000. Transfusion-aquired, autochthonous human babesiosis in Japan: isolation of Babesia microti-like parasites with hu-RBC-SCID mice. J. Clin. Microbiol., 38: 4511-4516.
14) Tsuji, M., Arai, S., Nakamura, Y., Kim, S-J., Cho, S.H., He, F.Q., Ishihara, C. 1999. Preparation of anbibodies directed to the Babesia ovata- or Theileria sergenti-parasitized erythrocytes. J. Vet. Med. Sci., 61(1): 73-6.
15) Nakaya, Y., Nakaya, T., Hagiwara, K., Momiyama, N., Kagawa, Y., Taniyama, H., Ishihara, C., Sata, T., Kurata, T., Ikuta, K. 1999. High susceptibility of mongolian gerbil (Meriones unguiculatus) to Borna Disease Virus. Vaccine, 17: 480-489.
16) Zheng, Y.H., Sentsui, H., Sugita, M., Nakaya, T., Kishi, M., Hagiwara, K., Inoshima, Y., Ishihara, C., Kono, Y., Lu, J.L., Ikuta, K. 2000. Replication ability in vitro and in vivo of equine infectious anemia virus avirulent Japanese strain. Virology 266(1):129-139.
17) Hagiwara, K., Kuribayashi, Y., Iwai, H., Azuma, I., Tokura, S., Ikuta, K., Ishihara, C. 1999. A sulfated chitin inhibit the hemagglutination by Theileria sergenti merozoites. Carbohydrate Polymers 39: 245-248.
1）新井智、辻正義、石原智明、2004、バベシア症、共通感染症ハンドブック、日本獣医師会共通感染症対策委員会編、（社）日本獣医師会、東京、PP190-191.
2）新井智、辻正義、石原智明、2004、バベシア、新興再興感染症 SARSの教訓、岡部信彦編、からだの科学増刊、日本評論社、東京、pp122-125. |
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